All Boss Materials in Diablo 4 and the Best Farming Locations

In Diablo 4, the late-game grind is intense, especially when preparing to face the challenging "ladder bosses." These formidable foes drop Unique Diablo 4 Items and are highly sought after by players striving for the best gear. However, summoning these bosses requires farming specific materials scattered throughout the game's world. This guide will walk you through the materials required for each boss in Diablo 4, where to find them, and how to optimize your farming routes.

 

Every Boss Material in Diablo 4

 

Summoning ladder bosses requires different materials based on the World Tier level you're playing. Some bosses can only be summoned in World Tier III or World Tier IV, while others appear at higher difficulties such as Tormented Tier. Let's break down the bosses and the materials you need for each, along with the best farming locations to gather them.

 

1. Grigoire, The Galvanic Saint

 

    Materials:

        Living Steel

            World Tier III: 2x Living Steel

            World Tier IV: 5x Living Steel

            Tormented: 15x Living Steel

    Best Farming Location: The most reliable way to farm Living Steel is through Helltide Tortured Gift Chests. These chests spawn during Helltide events and contain valuable materials, including Living Steel. Focus on areas with a high density of enemies, as clearing these zones quickly increases your chances of finding Tortured Gifts.

 

2. Echo of Varshan

 

    Materials:

        Malignant Hearts

            World Tier III: 2x Malignant Hearts

            World Tier IV: 5x Malignant Hearts

            Tormented: 15x Malignant Hearts

    Best Farming Locations:

        Helltide Events: These events are an excellent way to collect Malignant Hearts, as both normal and elite enemies can drop them.

        Whispers of the Dead Caches: Completing these quests rewards caches that often contain Malignant Hearts.

 

3. Beast in the Ice

 

    Materials:

        Distilled Fear

            World Tier IV: 9x Distilled Fear

            Tormented: 27x Distilled Fear

    Best Farming Location: The fastest way to farm Distilled Fear is by completing Tier 30+ Nightmare Dungeons. These dungeons not only drop high-tier gear and Diablo 4 Gold, but they also offer a consistent supply of Distilled Fear when completed at higher tiers.

 

4. Lord Zir

 

    Materials:

        Exquisite Blood

            World Tier IV: 9x Exquisite Blood

            Tormented: 27x Exquisite Blood

    Best Farming Locations:

        World Bosses: These massive enemies drop Exquisite Blood, especially at higher tiers.

        Legion Events: These timed events feature waves of enemies and often drop boss materials, including Exquisite Blood.

        Helltide Bosses: These enemies appear in Helltide zones and are a reliable source of Exquisite Blood.

 

5. Duriel, King of Maggots

 

    Materials:

        World Tier IV:

            2x Mucus-Slick Egg

            2x Shard of Agony

        Tormented:

            6x Mucus-Slick Egg

            6x Shard of Agony

    Best Farming Locations:

        Mucus-Slick Egg: You'll find this material by farming the Echo of Varshan and World Bosses.

        Shard of Agony: To get Shard of Agony, you'll need to farm Grigoire or World Bosses. Both have a high chance of dropping the material, especially in higher World Tiers.

 

6. Andariel, Maiden of Anguish

 

    Materials:

        World Tier IV:

            2x Pincushioned Doll

            2x Sandscorched Shackles

        Tormented:

            6x Pincushioned Doll

            6x Sandscorched Shackles

    Best Farming Locations:

        Pincushioned Doll: This material can be farmed from Beast in the Ice and World Bosses. Both have a relatively high drop rate for this item.

        Sandscorched Shackles: The best way to obtain this material is by farming Lord Zir or taking on World Bosses in high-difficulty tiers.

 

Universal Material: Stygian Stone

 

In addition to the boss-specific materials mentioned above, you'll need Stygian Stones to summon Tormented versions of these bosses. For every boss fight, you'll require one Stygian Stone along with the necessary materials. This means that as you farm for specific boss materials, you should also be on the lookout for Stygian Stones.

 

    Best Farming Location: The most efficient way to collect Stygian Stones is by completing the newly introduced Infernal Hordes Mode. To farm these Stones, you need to complete Tier 7 and higher challenges, as the enemies in these tiers are tougher but drop the best loot. In this mode, you'll face hordes of enemies that give higher rewards, making it ideal for acquiring Stygian Stones.

 

Final Thoughts

 

Farming boss materials in Diablo 4 is a crucial step in summoning the most powerful bosses and obtaining the rarest Diablo 4 Items. Whether you're after the perfect gear or want to earn a significant amount of Diablo 4 Gold, these bosses and their materials are central to your endgame progression. By focusing on the best farming locations and optimizing your routes, you can quickly gather the materials you need to summon ladder bosses and claim their valuable rewards.